Get the Best Antibiotics for Sinusitis Infection

Antibiotics are used to medicate sinus infections, whether acute or chronic sinusitis. The difference is in the dosage. Since acute sinus infections inflict a person for a short period of time only, the antibiotic dosage is commonly just one round of seven days. Dosage for chronic infections may take several weeks, and is likely to repeat throughout the year.

While you can get some antibiotics over the counter, it is best to get checked up by your doctor first and get a prescription.

Survey Says

A survey conducted on the usage of the antibiotics for sinusitis shows that many take antibiotics from the penicillin family. Macrolides and cephalosporins come next.


If the number of users is an indication, then Amoxicillin is probably the best antibiotics for sinus infection. It belongs to the penicillin family.

Amoxicillin works by affecting the metabolism of bacteria. It slows it down, alongside increasing the production of your body’s enzymes. Eventually, the bacteria weakens and is killed off.

Studies peg the effectiveness of Amoxillin in curing sinus infections at almost 89%. This is for acute sinusitis only. Chronic ones may experience different levels of effectiveness.

Amoxicillin should be taken every 8 hours or 12 hours, at 250 milligrams or 500 milligrams respectively. Children are given less dosage, depending on their weight and age.

Best Antibiotics for Sinusitis InfectionThe drug is available in tablet, liquid and chewable tablet forms. It doesn’t matter if you’ve eaten when you take it.

There may be some side effects to taking amoxicillin. This includes vomiting, diarrhea, nausea and dryness of mouth. In certain cases, there may even be convulsions, anxiety, dizziness, rash, jaundice and liver irritation. Often times, these side effects go away after a day.

Complications may arise if you are pregnant, nursing or suffering from liver or kidney diseases. The best antibiotics for sinus infection may also conflict with taking anti-gout medications, oral contraceptives, estrogen and other antibiotics. Always consult your doctor first before starting medication.


Augmentin is a kind of penicillin, and follows Amoxicillin as the best antibiotics for sinus infection. Its effectiveness ranges from 93% to 94%, depending on the severity of infection.

Dosage ranges from 250 to 500 milligrams, every 8 or 12 hours respectively. This may be increased at your doctor’s advice for severe cases. The drug can be bought as a tablet, chewable tablet or liquid solution.

If you have a sensitive digestive system, it is best to take food first before medicating with Augmentin. Otherwise, it is okay to take the medicine on an empty stomach.

Vomiting, diarrhea, stomach irritation, skin rash and headaches may be experienced while on Augmentin. Sometimes, side effects can be as severe as bloody or watery stools, weakness, yellow or peeling skin and a loss of appetite. If you experience any of these side effects, consult with your doctor as soon as possible.


Vantin or cefpodoxime ranks third amongst the best antibiotics for sinusitis. Unlike the first two, vantin is a type of cephalosporin. The effectiveness of the prescribed 100 to 400 milligram doses is at about 87% for adults and young adults.

Adults are generally given the tablet form of this medicine, while children are prescribed the liquid form. It is necessary to eat first before taking Vantin, especially when taking the tablet form.

Vantin comes with the common side effects of taking the best antibiotics for sinus infection. This includes stomach irritation, vomiting, nausea, diarrhea and headaches. In severe cases, you may experience bloody or watery stool, bleeding or bruising, heart palpitations, and general weakness. If you experience any of these sinusitis symptoms, consult your doctor as soon as possible.

Ideally, your doctor shouldn’t prescribe Vantin without asking you if you have allergies to cephalosporin antibiotics, or if you are suffering from any kidney or stomach disease. The doctor should also know if you are taking any other medication, especially cancer and antiviral medications.


Ceftin or cefuroxime is also a type of cephalosporin, given in dosages of 250 to 500 milligrams. Children are given less, depending on their weight and age. The drug has an 84% effectiveness rating in curing acute or chronic sinus infections.

The drug comes in tablet or liquid form. The tablet can be taken without food. The liquid form should be taken only after eating though.

As with the other best antibiotics for sinus infections, stomach irritation, diarrhea, joint pain, itching and headaches may arise from taking Ceftin. In serious cases, you may experience general weakness, jaundice, weight loss, urination problems and heart palpitations. Talk to your doctor if you experience any of these symptoms.


Zithromax or azithromycin is the only macrolide in this list of best antibiotics for sinus infection. With this drug, bacteria cells are inhibited from producing protein, which would eventually kill them off. The drug is said to work with almost 75% effectiveness. Its advantage is that it can be taken by almost everyone, even those with allergies to antibiotics.

Also, unlike the rest, the medicine is only given for three days, at one 500 milligram dosage per day. It comes in capsule, tablet, liquid and injection form.

Best Antibiotics for Sinusitis Infection

An odd side effect of zithromax is that it increases your skin’s sensitivity to the sun. You sunburn easier while taking the drug so keep off the sun and tanning beds. Other side effects are stomach irritation, diarrhea, headaches and dizziness.

Severe side effects can include abdominal tenderness, difficulty breathing, swelling of extremities, fever, and bloody or watery stools. Check with your doctor if you experience any of these symptoms. This could save your life.
Zithromax can also conflict with other medications you may be taking. This includes tetrabenazine, nilotinib, propafenone, dofetilide, rifampin, pimozide, nelfinavir, anticoagulants and heart disease medications. You may also experience problems with the drug if you are allergic to macrolide or ketolide antibiotics, or are suffering from liver or kidney diseases. Make sure to disclose your full medical profile to your doctor first before taking zithromax. It is best to keep your doctor informed if you want to stay safe.

You can read what is sinusitis and how to treat a sinus infection here for better understanding

This entry was posted in Sinus, Sinus Infection, Sinusitis. Bookmark the permalink.